The Toowoomba Hospital Foundation was formed under the Hospitals Foundations Act 1982. The Foundation was originally formed as the Toowoomba Health Services Foundation. In October 1991 it was changed to the Darling Downs Health Services Foundation to take on a regional perspective. In October 1996 the name was changed to the Toowoomba Hospital Foundation.

The Toowoomba Hospital Foundation is a non-profit, charitable organisation that is a statutory body responsible to the Queensland Minister for Health however receives no government funding. Managed by a voluntary Board of Directors, the Foundation has a staff that includes Chief Executive Officer, Peter Rookas; Executive Support Officer, Anna-Louise Sauverain and Administrative Officer, Pamela Hammond.

The Toowoomba Hospital Foundation is governed by a Board of Directors, serving voluntarily, appointed by the Governor in Council. This board consists of business, community and university identities plus senior health professionals. Prominent local businessman Raymond Taylor is the Chair of the Board that includes other leading local business and community leaders Lewis Rowling, Andrew Wielandt, Roslyn Reilly, Horst Brosi, Brenda Tait, Peter Sedl as well as senior executive of the Darling Downs - West Moreton Health Service District,  Executive Director Toowoomba Hospital & Executive Director Medical Services, Dr Peter Bristow; Manager Clinical Operations Rural Division, Judy March and Shayne Stenhouse as Secretary.

From a very humble beginning in 1989, the Toowoomba Hospital Foundation has evolved into one of the most recognised and supported charities in the Toowoomba and Darling Downs region and today provides outstanding support for the Toowoomba Hospital and associated health services of the region.

The Foundation assists the hospital and health services in facilitating donations from the corporate sector, service clubs and general community. Fund raising events are also conducted with many being established as major events in their own right including charity golf days, cinema and theatre evenings as well as being associated with a number of major events conducted by other organisations such as the Chronicle Bridal Fair and A Christmas Wish. The establishment of the Toowoomba Hospital Children’s Appeal has been a major step forward for the Foundation and the appeal has become one of the most important annual projects for the hospital.

Since the inception of the Foundation, more than $1.5 million in equipment and resources has been donated to the hospitals and health services of the region and that support continues to grow from year to year.